6 HRT Statistics in 2025


Doctors and menopausal women have varying opinions about Hormone Replacement therapy. The Women’s Health Initiative information influences women’s attitude toward HRT. Its published associated risks, like breast cancer, heart disease, stroke, and blood clot make women hesitant in using HRT for menopause treatment. 

Doctors lower their HRT prescription because of its related health risks. This translates to lower usage of the treatment despite newer research results of its efficacy to younger menopausal women with appropriate risk assessment. 


This article highlights the present and emerging HRT statistics. How product developments provide less health compromise to menopause women, and how proper education and awareness influence medical choices. 

1. The percentage of menopausal women using hormone replacement therapy declined yearly by 0.23%.


Menopausal (1.8 %) and postmenopausal (4.7%) women posted a decrease in use of hormone replacement therapy. According to Stephanie S. Faubion (MD, MBA, NCMP, IF, Mayo Clinic Center for Women’s Health director and The Menopause Society medical director), misinformation is the top reason why women are hesitant in taking HRT.


Additionally, the availability of updated HRT research across online and offline resources will educate women about the pros and cons of this treatment. 

2. HRT leads all compounding therapeutic areas in the US, with a market value forecasted to reach over 67 billion over the next 10 years. 


The US experiences the rise of an aging population. The Population Reference Bureau projected that Americans ages 65 and older will increase by 47% in 2050. Also, innovation in medical research and changes in regulatory guidelines will drive the HRT market to grow at a compound annual growth of 6% in 2030. 


The growing importance of aging quality life encourages women to look for menopause medical interventions. Moreover, the country is dominated by major pharmaceutical companies that continuously invest in research and development to provide better health and life care for women. 

3. Women using bioidentical hormone therapy (BHT) increases by 5%-10% yearly.


Bioidentical hormone therapy is processed hormones (estrogen, progesterone, and testosterone) from plants. These hormones mimic natural hormones so the body will recognize them the way it recognizes natural hormones. 


According to the Natural Institutes of Health research, women favor this treatment because it’s natural and prescribed as biomedical. Also, the clinical approach of providers offer menopausal women holistic treatment of their symptoms. 


However, bioidentical hormone therapy has risks. Women with or at high risk of blood clotting disorders, cardiovascular disease, breast cancer, and stroke are not allowed to take. 

4. Women using transdermal estrogen increases by 6.8% yearly.


Transdermal estrogen therapy is used to treat moderate to severe menopause symptoms. It’s available as patch and gel and applied directly to the skin. Patches are changed once or twice a week (depending on the brand) and gel is applied daily. 


Women prefer this type of treatment because it provides more consistent estrogen levels and doesn’t affect the liver compared to oral estrogen. More importantly, transdermal estrogen therapy has flexible dosing options and is easy to use. 

5. 80% of menopausal women reported that they heard HRT, with 55% receiving information from physicians. 


Menopause discussion and its treatment are less talked about in clinical and social settings. As a result, most menopausal women’s information about HRT comes from personal research or through the media. Also, limited patient-doctor communication and the patient’s uneasiness or difficulty in describing their symptoms create an information gap. 


Moreover, according to study, HRT discussions are frequently initiated by female physicians. This means that women are more comfortable sharing their symptoms and exploring treatment options to people who have similar experiences with them.

6. 20%-30% of menopausal women express fear or hesitation in using HRT because of its potential risks and side effects.


Apart from its potential health issues, misinformation and outdated medical advice from doctors, media, and peers make women avoid HRT. Additionally, some women fear the side effects, like weight gain or mood swings and others believe menopause is a natural phase that doesn’t require medical intervention. 


Sources


Management of Menopausal Symptoms


Menopause: A Natural Part of Aging


BHRT vs HRT for Menopause: Understanding the Difference


Management of Perimenopausal and Menopausal Symptoms


Menopausal Hormone Therapy, an Ever-Present Topic: A Pilot Survey about Women’s Experience and Medical Doctors’ Approach


Risks and Benefits of MHT

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