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Menopause Testing

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Menopause testing measures hormone levels to determine if a woman is approaching or has reached menopause. This checks follicle-stimulating hormone (FSH). FSH is produced by the pituitary gland, located at the base of the brain. It's important in regulating men and women's reproductive processes. For women, it stimulates the growth and maturation of ovarian follicles (which contain eggs) during the menstrual cycle. For men, it stimulates the growth and maturation of ovarian follicles (which contain eggs) during the menstrual cycle. As women age, the ovaries start producing less estrogen and progesterone. The decline of these hormones lead to hormonal fluctuations that result in irregular periods, vaginal dryness, mood changes, headaches, night sweats, and hot flashes. These symptoms are common in perimenopause. Healthcare providers run hormone testing to determine a woman’s stage in menopause. Traditionally, menopause is diagnosed based on a woman’s symptoms and the absence of ...

Oral vs Transdermal Menopause Treatment

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The 2 common ways of administering menopausal therapy are oral and transdermal. While different, their efficacies are notable in treating various menopause symptoms. Mayo Clinic's published study showed oral estrogen therapy is effective in reducing hot flashes and night sweats by 70%-80%. Also, the British Journal of General Practice published study revealed transdermal estradiol had the highest probability of being the most effective treatment for vasomotor symptoms compared with placebo. However, these treatments come with side effects and associated health risks. Read on to learn more about oral and transdermal menopause therapy. Availability Oral menopause therapy products are available in the United States, Canada, United Kingdom, European Union, Australia, India, China, Japan, and South Africa. Transdermal menopause hormone therapy products are licensed in most European countries, North America, Australia, New Zealand, and several Asian countries (China, India, and Pakistan)...

4 Reasons To Avoid HRT

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Doctors and menopausal women have different opinions about HRT. The Women’s Health Initiative information influences women’s attitudes toward HRT. Its published associated risks, like breast cancer, heart disease, stroke, and blood clots make women and doctors hesitant to use HRT for menopause treatment. As a result, the percentage of menopausal women using hormone replacement therapy declined yearly by 0.23% (from 2007 to 2023).  However, a part of this statistic doesn’t come from HRT’s associated health risks. Some menopausal women have existing health conditions and health histories that keep them from trying HRT. Here are some: 1. Breast Cancer Women with a history of breast cancer are advised against using HRT. Estrogen stimulates the growth of some breast cancer cells and increases the risk of cancer recurrence. For example, a woman previously treated for estrogen receptor-positive breast cancer will have a heightened risk if she undergoes HRT. A 2021 review published in Brea...

What is Tibolone?

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  Tibolone is a synthetic steroid hormone that has estrogen, androgen, and progestogen properties. It restores the imbalanced female hormones during menopause and manages night sweats and hot flashes. Also, this is prescribed to women who missed their periods for a year to prevent osteoporosis. Tibolone is produced by Organon Pharmaceuticals in West Orange, New Jersey. It comes in tablets and has been used in Europe for 2 decades as treatment and prevention of postmenopausal osteoporosis and postmenopausal symptoms. Additionally, it is approved in 90 countries to manage menopause symptoms and in 45 countries to prevent osteoporosis development. Regulation The FDA didn’t approve tibolone for use in the United States (Organon Pharmaceuticals received a ‘Not Approvable’ letter from the FDA). The treatment’s increased breast cancer and stroke risks, and its androgenic effects (it can act like male hormones in the body) are the factors contributed to FDAs decision. Tibolone is approved ...

Transdermal Hormone Therapy

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Transdermal menopause hormone therapy is administered through the skin using patches, gels, creams, and sprays. This treatment absorbs estrogen and sometimes progestin (if necessary) directly into the bloodstream. The hormones penetrate the skin barrier and enter the blood vessels, ensuring a steady absorption into the bloodstream. It's available in: Patches Applied on a clean and dry skin of the lower abdomen, upper thighs, and buttocks. Changed according to the prescribed schedule. Gel and Cream Applied daily on arms, legs, shoulders, or abdomen. Requires drying time before covering with clothing to ensure proper absorption. Spray Applied daily through metered-dose spray on the forearm (between the elbow and the wrist) and inner thigh. Requires drying time before covering with clothing to ensure proper absorption. Transdermal Efficacy Transdermal menopause hormone therapy benefits the liver and digestive system because it bypasses first-pass metabolism in the liver and avoids dir...